Selected Publications
Non-coding sequence variation reveals fragility in interleukin 2 feedback circuitry and shapes autoimmune disease risk
Simeonov, D.R.+, Park, K.+, Cortez, J. T., Young, A., Li, Z., Nguyen, V., Umhoefer, J., Indart, A., Woo, J.M., Anderson, M.S., Tsang, J.S., Germain, R.N.*, Marson, A.M.*, Wong, H.S.* BioRxiv, 2023
+Equal contribution
*Co-senior authorship
A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells
Wong, H.S., Park, K., Gola, A., Baptista, A.P., Miller, C.H., Deep, D., Lou, M., Boyd, L.F., Rudensky, A.Y., Savage, P.A., Altan-Bonnet, G., Tsang, J.S., Germain, R.N.
Cell, 2021
Highlighted in Volume control: Turning the dial on regulatory T cells, Brown, C.C., and Gottschalk, R.A, Cell, 2021
Mesoscale T cell antigen discrimination emerges from intercellular feedback
Wong, H.S. & Germain, R.N.
Trends in Immunology, 2021
Best of 2021 Collection: Trends in Immunology
Commensal-driven immune zonation of the liver promotes host defence
Gola, A., Dorrington, M.G., Speranza, E., Sala, C., Shih, R.M., Radtke, A.J., Wong, H.S., Baptista, A.P., Hernandez, J.M., Castellani, G., Fraser, I.D.C., Germain, R.N.
Nature, 2021
Robust control of the adaptive immune system
Wong, H.S. & Germain, R.N.
Seminars in Immunology, 2018